Molecular phylogeny of modern coxsackievirus A16

David, Perera and Yuwana, Podin and Mong, How Ooi and Ali, Zaki (2007) Molecular phylogeny of modern coxsackievirus A16. Archives of Virology, 152 (6). pp. 1201-1208. ISSN 1432-8798

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Official URL: http://link.springer.com/article/10.1007/s00705-00...

Abstract

A phylogenetic analysis of VP1 and VP4 nucleotide sequences of 52 recent CVA16 strains demonstrated two distinct CVA16 genogroups, A and B, with the prototype strain being the only member of genogroup A. CVA16 G-10, the prototype strain, showed a nucleotide difference of 27.7–30.2% and 19.9–25.2% in VP1 and VP4, respectively, in relation to other CVA16 strains, which formed two separate lineages in genogroup B with nucleotide variation of less than 13.4% and less than 16.3% in VP1 and VP4, respectively. Lineage 1 strains circulating before 2000 were later displaced by lineage 2 strains.

Item Type: Article
Uncontrolled Keywords: Molecular phylogeny, coxsackievirus A16, Hand, foot, and mouth disease (HFMD), unimas, university, universiti, Borneo, Malaysia, Sarawak, Kuching, Samarahan, ipta, education, research, Universiti Malaysia Sarawak
Subjects: R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
Divisions: Academic Faculties, Institutes and Centres > Institute of Health and Community Medicine
Faculties, Institutes, Centres > Institute of Health and Community Medicine
Depositing User: Karen Kornalius
Date Deposited: 26 Sep 2016 23:14
Last Modified: 26 Sep 2016 23:14
URI: http://ir.unimas.my/id/eprint/13623

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