Identification Of Protein Partners Of The Human Nucleophosmin (Npm1) Using Bioinformatics Analysis

Anis Sabrina, Jubaidi (2018) Identification Of Protein Partners Of The Human Nucleophosmin (Npm1) Using Bioinformatics Analysis. [Final Year Project Report] (Unpublished)

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Abstract

Nucleophosmin, NPMl can be found in the leukaemia and cancer study. In this paper, NPMl is used as a target protein to search its protein partner and the possible interaction between them. The method used is by using bioinfonnatic analysis multiple alignment, 3D modelling, model assessment, structure neighbour, candidate partners, and structural docking. The tool revealed 4KZX and 4KZY as the structural neighbours and possible candidate partners. There are around seven candidate partners of NPMI has been discovered and the proteins that has been discovered has the same expression as the NPM I.

Item Type: Final Year Project Report
Additional Information: Project report (B.Sc.) -- Universiti Malaysia Sarawak, 2018.
Uncontrolled Keywords: Nucleophosmin, protein-protein interaction, sequence alignment, structural docking
Subjects: Q Science > Q Science (General)
Divisions: Academic Faculties, Institutes and Centres > Faculty of Resource Science and Technology
Depositing User: Patrick
Date Deposited: 27 Apr 2021 11:14
Last Modified: 27 Apr 2021 11:14
URI: http://ir.unimas.my/id/eprint/35175

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