Facile Synthesis and Applications of Flavonoid-heterocyclic Derivatives

Saba, Farooq and Zainab, Ngaini (2024) Facile Synthesis and Applications of Flavonoid-heterocyclic Derivatives. Current Topics in Medicinal Chemistry, 25 (1). pp. 47-62. ISSN 1873-4294

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Official URL: https://www.eurekaselect.com/article/140835

Abstract

Abstract: Flavonoids belong to the polyphenol group that naturally exists in fruits, vegetables, tea, and grains. Flavonoids, as secondary metabolites, show indispensable contributions to biolog-ical processes and the responses of plants to numerous environmental factors. The bioactivity of flavonoids depends on C6-C3-C6 ring substitution patterns that exhibit bioactive antioxidant, an-timicrobial, antifungal, antitumor, and anti-inflammatory properties. The synthesis of flavonoids has been reported by various methodologies. Therefore, the present review systematically sum-marizes the synthesis of recent heterocyclic flavonoid derivatives via facile synthetic approaches since the research in flavonoids is useful for therapeutic and biotechnology fields.

Item Type: Article
Uncontrolled Keywords: Activities, bioavailability, disease, flavonoids, flavone, synthesis.
Subjects: Q Science > Q Science (General)
Q Science > QD Chemistry
Divisions: Academic Faculties, Institutes and Centres > Faculty of Resource Science and Technology
Faculties, Institutes, Centres > Faculty of Resource Science and Technology
Depositing User: Ngaini
Date Deposited: 27 Dec 2024 06:56
Last Modified: 27 Dec 2024 06:56
URI: http://ir.unimas.my/id/eprint/47066

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