“A stitch in time saves nine” : managing congenital nephrotic syndrome in resource-limited circumstances

Karmila, Abu Bakar and Justin Wang, Qi Yuee and Amalina Huda, Amir Hamzah and Charles, Lai Dekun and Caroline Eng, Siew Yin (2022) “A stitch in time saves nine” : managing congenital nephrotic syndrome in resource-limited circumstances. MJM Case Reports Journal, 1 (2). pp. 156-158. ISSN 2948-3859

PDF A stitch.pdf Download (35kB)

Abstract

We report a case of congenital nephrotic syndrome. Our patient presented with sepsis-like illness and acute kidney injury during the neonatal period. Subsequent urine analysis showed persistent heavy proteinuria with concomitant hypoalbuminaemia and clinical anasarca. Screening for congenital infections was negative. Diuresis was initially induced with daily albumin infusion. Subsequently, administration of furosemide combined with amiloride was adopted as albumin-sparing strategies. Both angiotensin�converting enzyme inhibitor and non-steroidal anti�inflammatory drugs were started after 4 weeks of life. Such treatment strategies resulted in a significant reduction in the need for albumin infusion, thus allowing better preservation of the venous estate and improving quality of life with a reduced need for inpatient care.

Actions (For repository members only: login required)

View Item