Human Leukocyte Antigen (HLA) region in human population studies

Timothy Adrian, Jinam (2017) Human Leukocyte Antigen (HLA) region in human population studies. In: Evolution of the Human Genome I. Springer Japan, Tokyo, pp. 173-180. ISBN 978-4-431-56601-4

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Abstract

Human leukocyte antigen (HLA) genes function to present processed antigenic peptides to immune cells, hence their major importance in eliciting immune responses. HLA genes have been extensively studied for their disease associations and pre-/posttransplantation applications. Due to their highly polymorphic nature, HLA genes are also used for population genetic studies. This chapter summarizes the structure, functions, nomenclature, genotyping methods, and population genetic applications of the HLA system.

Item Type: Book Chapter
Uncontrolled Keywords: Human Leukocyte Antigen (HLA), Major histocompatibility complex (MHC), Immune system, Population genetics
Subjects: Q Science > QH Natural history > QH426 Genetics
Divisions: Academic Faculties, Institutes and Centres > Faculty of Medicine and Health Sciences
Faculties, Institutes, Centres > Faculty of Medicine and Health Sciences
Depositing User: Joseph Jinam
Date Deposited: 25 Jul 2023 07:12
Last Modified: 25 Jul 2023 07:12
URI: http://ir.unimas.my/id/eprint/42420

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