Seroprevalence of Nipah Virus Infection in Peninsular Malaysia

Yong, Ming Yen and Lee, Soo Ching and Romano, Ngui and Yvonne Ai, Lian Lim and Maude E., Phipps and Chang, Li Yen (2020) Seroprevalence of Nipah Virus Infection in Peninsular Malaysia. The Journal of Infectious Diseases., 221 (Supp.4). S370-S374. ISSN 1537-6613

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Abstract

Nipah virus (NiV) outbreak occurred in Malaysia in 1998. The natural host reservoir for NiV is Pteropus bats, which are commonly found throughout Malaysia. Humans become infected when NiV spills over from the reservoir species. In this study, NiV serosurveillance in Peninsular Malaysia, particularly among the indigenous population, was performed. The collected samples were tested for presence of NiV antibodies using a comparative indirect enzyme-linked immunosorbent assay based on the recombinant NiV nucleocapsid (rNiV-N) protein. We found that 10.73% of the participants recruited in this study had antibodies against rNiV-N, suggesting possible exposure to NiV.

Item Type: Article
Uncontrolled Keywords: Nipah virus; serosurveillance; Malaysia; indigenous population; comparative indirect ELISA; nucleocapsid protein.
Subjects: Q Science > QR Microbiology
Divisions: Academic Faculties, Institutes and Centres > Faculty of Medicine and Health Sciences
Faculties, Institutes, Centres > Faculty of Medicine and Health Sciences
Depositing User: Gani
Date Deposited: 05 Jul 2023 02:41
Last Modified: 05 Jul 2023 02:41
URI: http://ir.unimas.my/id/eprint/42133

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