Discerning the origins of the Negritos, First Sundaland People : deep divergence and archaic admixture

Timothy Adrian, Jinam and Maude E., Phipps and Farhang, Aghakhanian and Partha P., Majumder and Francisco, Datar and Mark, Stoneking and Hiromi, Sawai and Nao, Nishida and Katsushi, Tokunaga and Shoji, Kawamura and Keiichi, Omoto and Naruya, Saitou (2017) Discerning the origins of the Negritos, First Sundaland People : deep divergence and archaic admixture. Genome Biology and Evolution, 9 (8). pp. 2013-2022. ISSN 1759-6653

PDF Discerning the Origins.pdf Download (35kB)

Abstract

Human presence in Southeast Asia dates back to at least40,000 years ago, when the current islands for meda continental shelf called Sundaland. In the Philippine Islands, Peninsular Malaysia, and Andaman Islands, there exist indigenous groups collectively called Negritos whose ancestry can be traced to the “First Sundaland People.” To understand the relationship between these Negrito groupsand theirdemographic histories, wegeneratedgenome-wide single nucleotide polymorphism datain the Philippine Negritos and compared them with existing data from other populations. Phylogenetic tree analyses show that Negritos are basal to other East and Southeast Asians, and that they diverged from West Eurasians at least 38,000 years ago. We also found relatively high traces of Denisovan admixture in the Philippine Negritos, but not in the Malaysian and Andamanese groups, suggesting independent introgression and/or parallel losses involving Denisovan introgressed regions. Shared genetic loci between all three Negrito groups could be related to skin pigmentation, height, facial morphology and malarial resistance. These results show the unique status of Negrito groups as descended from the First Sundaland People.

Actions (For repository members only: login required)

View Item