Ahmad Faizal, Jelani and Gabrielle Ruth Anisah, Fromming and Dayang Erna Zulaikha, Awang Hamsin and Mohammad Zulkarnaen, Ahmad Narihan (2022) The toxic effects of p-Cresyl Sulfate on bone metabolism. In: 6th International Conference on Molecular Diagnostics and Biomarker Discovery (MDBD 2022): Building Resilience in Biomedical Research, 11-13 October 2022, Penang, Malaysia.
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Abstract
Background p-Cresyl Sulfate (pCS) is a uremic toxin that has been implicated in kidney disease, cardiovascular risks, endothelial dysfunction and neuropathies. In chronic kidney disease (CKD), pCS progressively accumulates in the body as the dysfunctional kidneys have a reduced ability to excrete toxins normally. pCS accumulated as a consequence of CKD cannot be removed from th body through dialysis, hence leading to further accumulation. This ultimately leads to bone loss which correlates with the worsening of CKD. As such, pCS could play a part in the development of bone loss with CKD. The objective of this review is to further understand the comprehensive effects pCS has on the bone.
| Item Type: | Proceeding (Paper) |
|---|---|
| Additional Information: | Conference Proceedings – 6th International Conference on Molecular Diagnostics and Biomarker Discovery (MDBD 2022): Building Resilience in Biomedical Research |
| Uncontrolled Keywords: | p-Cresyl Sulfate (pCS), uremic toxin, chronic kidney disease (CKD). |
| Subjects: | R Medicine > R Medicine (General) R Medicine > RB Pathology |
| Divisions: | Academic Faculties, Institutes and Centres > Faculty of Medicine and Health Sciences Faculties, Institutes, Centres > Faculty of Medicine and Health Sciences |
| Depositing User: | Gani |
| Date Deposited: | 01 Feb 2023 03:06 |
| Last Modified: | 03 May 2023 01:57 |
| URI: | http://ir.unimas.my/id/eprint/41217 |
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