Characterization of an unusual adenovirus strain, Sibu 97

Perera, David (2005) Characterization of an unusual adenovirus strain, Sibu 97. PhD thesis, Universiti Malaysia Sarawak, (UNIMAS).

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Abstract

n adenovirus isolate, SIBU97, associated with an unexplained cluster of deaths of children with fatal acute myocardial dysfunction in Sarawak was characterized and compared with other human adenoviruses. The research is study the sequence comparisons with GenBank of portions of the SIBU97 genome that include the E1, E2, and E3 transcript regions showed that it shared >94% identity to human species B adenoviruses and simian adenovirus type 21. A comparison of restriction digest profiles of SIBU97 with prototype species B adenoviruses and several European Ad21 variants revealed profiles generated with Bam H1, Sma ! and Kpn 1 that differed from the other adenoviruses but were closely related to prototype Ad21.

Item Type: Thesis (PhD)
Additional Information: Thesis (Ph.D.) - Universiti Malaysia Sarawak, 2005.
Uncontrolled Keywords: Medical virology, Universiti Malaysia Sarawak, UNIMAS, Institute of Health and Community Medicine, IHCM, IPTA, education, sarawak, malaysia, kuching, samarahan, universiti, university, postgraduate, research
Subjects: Q Science > QR Microbiology
Divisions: Academic Faculties, Institutes and Centres > Institute of Health and Community Medicine
Faculties, Institutes, Centres > Institute of Health and Community Medicine
Depositing User: Karen Kornalius
Date Deposited: 07 Jul 2014 04:42
Last Modified: 22 Jun 2023 09:27
URI: http://ir.unimas.my/id/eprint/3835

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