Micro-Needle Integrated with Micro-Pump for Drug and Blood Deliveries in Polygonal Inner Structures of Micro-Channels

Yana Shaheera, Yunos (2020) Micro-Needle Integrated with Micro-Pump for Drug and Blood Deliveries in Polygonal Inner Structures of Micro-Channels. Masters thesis, Universiti Malaysia Sarawak (UNIMAS).

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Abstract

Blood is a complex suspension that demonstrates non-Newtonian rheological characteristics. The study of hemorheology has been of great interest in the fields of biomedical engineering and medical researches for many years. Micro-channel such as micro-needle has been an expanding medical technology in recent years due to their ability to penetrate tissue and deliver therapy with minimal invasiveness and patient discomfort. Micro-channel geometries have been used to study the inertial insertion focusing on behaviour of particles suspended as variations in design. The studies have enhanced fluid delivery in biomedical field. This research presents a comparison on dynamic characteristics of flow velocity and pressure losses in micro-needle using numerical and experimental analysis. The advancement of research is also conducted by integrating the micro-needles with micro-pump to improve their functions during fluid deliveries. The micro-needles with channel inner design of circle, square, hexagon and dodecagon came with various design parameters. These geometry studies had improved the flow performance and the efficiencies in delivering drug and blood using polygonal structured micro-needles.

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