Antimicrobial Activity Of Partially Purified Peptides Isolated From The Skin Secretions Of Bornean Frogs In The Family Of Ranidae

Muna, Binti Sabri and Elizabeth Jega, Anak Jenggut and Ramlah, Binti Zainudin and Zunika, Binti Amit (2018) Antimicrobial Activity Of Partially Purified Peptides Isolated From The Skin Secretions Of Bornean Frogs In The Family Of Ranidae. Malaysian Applied Biology, 47 (6). pp. 1-8. ISSN 0126-8643

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Abstract

The emergence of drug resistant bacteria has now become a major public health problem worldwide (Cohen, 2000; Kumarasamy et al., 2010; Sengupta et al., 2013). WHO report (2017) on global surveillance of antimicrobial resistance revealed a widespread development of resistance in both gram positive and gram negative bacteria which had threatened millions of people worldwide. A rapid increase in number of drug-resistant bacteria and incidence nosocomial infections pose a challenge to conventional therapies using existing antibiotics, leading to the need in finding alternative microbicides to control these infections (Lakshmaiah et al., 2015). Thus, a discovery of new and effective treatments that can replace current available antibiotics has become a critical area of research globally.

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