The Association Between N-Terminal B-Type Natriuretic Peptide and One Year Clinical Outcome in Patients with Acute Myocardial Infarction : A Multicenter Study

Asri, Said and Koh, Keng Tat and Tan, S.S.N. and Sim, P. P. and Tiong, L.L. and Ku, M. Y. and Wong, I. T. and Yong, K. Y. and Lau, K. T. and Chandan, D.B. and Fong, S. L. and Sia, T. L. L. and Shu, F.E.P. and Oon, Y.Y. and Khaw, C.S. and Ho, K. H. and Tan, C.T. and Khiew, Ning Zhan and Cham, Yee Ling and Voon, C.Y. and Nor Hanim, Mohd Amin and Fong, A.Y.Y. and Ong, T.K. (2018) The Association Between N-Terminal B-Type Natriuretic Peptide and One Year Clinical Outcome in Patients with Acute Myocardial Infarction : A Multicenter Study. International Journal of Cardiology, 273 (Supp). p. 1. ISSN 0167-5273

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Abstract

Background: NT-proBNP is a useful biomarker in the management of heart failure. However, there is conflicting evidence for the prognostic value of NT-ProBNP in acute myocardial infarction (AMI). Objectives: (1) To explore the association between NT-proBNP and 1-year cardiac related mortality in AMI patients. (2) To explore the association between NT-proBNP and 1-year risk of sudden cardiac death or ventricular arrhythmia, readmission for heart failure, readmission for acute coronary syndrome (ACS) and stroke. Methods: We conducted a multicenter, prospective observational study recruiting patients presenting with AMI between 1-August2016 to 31-January-2017, involving 1 cardiology referral center and 4 non-cardiology hospitals. NT-proBNP levels (Alere Triage®, US) were measured within 24 hours of AMI diagnosis. Patients were followed-up for 1 year.

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