Chee, Shee Chai (2017) Small Cell Transformation and T790M Mutation as Coresistance Mechanisms for First-line Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor (TKI) Therapy Failure. Journal of Thoracic Oncology, 12 (10). pp. 171-173. ISSN 1556-0864
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Official URL: http://www.jto.org/article/S1556-0864(17)30568-3/p...
Abstract
Discovery of the activating EGFR mutation gene has revolutionized the treatment of patients with NSCLC. Nevertheless, resistance to first-line EGFR tyrosine kinase inhibitors (TKIs) develops in most patients with EGFR-mutant NSCLC after a period of 9 to 13 months. Here, we reported a case of first-line EGFR TKI failure attributed to SCLC transformation and T790M mutation
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Medicine, tumor, unimas, university, universiti, Borneo, Malaysia, Sarawak, Kuching, Samarahan, ipta, education, research, Universiti Malaysia Sarawak |
| Subjects: | R Medicine > R Medicine (General) |
| Divisions: | Academic Faculties, Institutes and Centres > Faculty of Medicine and Health Sciences Faculties, Institutes, Centres > Faculty of Medicine and Health Sciences |
| Depositing User: | Karen Kornalius |
| Date Deposited: | 03 Jan 2018 07:10 |
| Last Modified: | 08 Jun 2022 07:56 |
| URI: | http://ir.unimas.my/id/eprint/19173 |
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