Chin, Sukfun and Jimmy, Fiona Beragai and Pang, Suhcem (2016) Fabrication of cellulose aerogel from sugarcane bagasse as drug delivery carriers. Journal of Physical Science, 27 (3). pp. 159-168. ISSN 16753402
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Abstract
Currently most of the aerogel-based drug delivery carriers are made from non-biodegradable materials, such as silica. In this study, highly porous cellulose aerogels with Brunauer-Emmett-Teller (BET) surface areas that varied between 22 m2 g-1 and 525 m2 g-1 were prepared from a sugarcane bagasse cellulose solution of various concentrations. The potential utility of cellulose aerogels as controlled release carriers was evaluated by loading methylene blue (MB) as a model hydrophilic drug. The MB loading capacity and release kinetic profiles of cellulose aerogels were observed to be substantially influenced by their BET surface areas. Under optimum conditions, a maximum loading capacity of 6.4 mg MB mg-1 cellulose aerogel was achieved with sustained release of MB from cellulose aerogels at physiological pH over a period of 23 h
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Aerogels; Cellulose; Controlled release; Drug carriers; Sugarcane bagasse, research, Universiti Malaysia Sarawak, unimas, university, universiti, Borneo, Malaysia, Sarawak, Kuching, Samarahan, ipta, education |
| Subjects: | Q Science > QD Chemistry |
| Divisions: | Academic Faculties, Institutes and Centres > Faculty of Resource Science and Technology Faculties, Institutes, Centres > Faculty of Resource Science and Technology |
| Depositing User: | Ibrahim |
| Date Deposited: | 16 Feb 2017 07:22 |
| Last Modified: | 24 May 2022 08:35 |
| URI: | http://ir.unimas.my/id/eprint/15302 |
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