Toxicity Screening of Dibenzothiophene on Early Vertebrate Development

Memarshall, M. Ongkudon (2015) Toxicity Screening of Dibenzothiophene on Early Vertebrate Development. [Final Year Project Report] (Unpublished)

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Abstract

Dibenzothiophene is a minor component of petroleum crudes, coal tars, shale oil and synthetic fuels which has a toxic property to mammals and aquatic verterbrates. This research was conducted to analyse the toxicity effects of dibenzothiophene on zebrafish (Danio rerio) embryos at every pre determined stage of its embryogenesis. Different concentration of dibenzothiophene was exposed to the embryos and several parameters (developmental effects) were chosen to be observed throughout the embryogenesis of D. rerio embryos. The results of this experiment shows that dibenzothiophene cause delay in D. rerio embryos morphogenesis. LCso ofdibenzothiophene for D. rerio embryo was also determined in this study by taking the average total mortality of the replicates which has nearest value to 50%. It was concluded that different concentrations of dibenzothiophene exert different severity ofdefects in D. rerio embryogenesis.

Item Type: Final Year Project Report
Additional Information: Project Report (B.Sc.) -- Universiti Malaysia Sarawak, 2015.
Uncontrolled Keywords: unimas, university, universiti, Borneo, Malaysia, Sarawak, Kuching, Samarahan, ipta, education, undergraduate, research, Universiti Malaysia Sarawak, Dibenzothiophene , Danio rerio, embryo, toxicity, embryogenesis.
Subjects: G Geography. Anthropology. Recreation > GE Environmental Sciences
Divisions: Academic Faculties, Institutes and Centres > Faculty of Resource Science and Technology
Faculties, Institutes, Centres > Faculty of Resource Science and Technology
Depositing User: Karen Kornalius
Date Deposited: 07 Mar 2016 01:00
Last Modified: 18 Aug 2023 08:36
URI: http://ir.unimas.my/id/eprint/10770

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