Items where Author is "Sim, S.P"

Siaw, Shi Boon and Sim, S.P (2015) Inhibitor of caspase-activated DNase expression enhances caspase-activated DNase expression and inhibits oxidative stress-induced chromosome breaks at the mixed lineage leukaemia gene in nasopharyngeal carcinoma cells. Cancer Cell International, 15 (54). ISSN 1475-2867

Cynthia Patricia, Nicholas and Sim, S.P (2012) Etoposide-induced apoptosis results in chromosome breaks within the AF9 gene: Its implication in chromosome rearrangement in leukaemia. Advances in Bioscience and Biotechnology, 3 (6). pp. 686-694.

Yee, P.H.C and Sim, S.P (2010) High cell density and latent membrane protein 1 expression induce cleavage of the mixed lineage leukemia gene at 11q23 in nasopharyngeal carcinoma cell line. Journal of Biomedical Science, 17 (77).

Liu, L.F. and Shyamal D., Desai and Li, Tsai-Kun and Mao, Yong and Mei, Sun and Sim, S.P (2006) Mechanism of Action of Camptothecin. Annals of New York Academy of Science, 922. ISSN 1749-6632

Li, D. and Zhao, B. and Sim, S.P and Li, T.K and Liu, A. and Liu, L.F. and LaVoie, E.J. (2003) 8,9-Methylenedioxybenzo[i]phenanthridines_ Topoisomerase I-Targeting activity and cytotoxicity. Bioorganic & Medicinal Chemistry, 11 (17). pp. 3795-3805.

Makhey, D. and Li, D. and Zhao, B. and Sim, S.P and Li, TK and Liu, A. and Liu, L.F. and LaVoie, E.J. (2003) Substituted benzo[i]phenanthridines as mammalian topoisomerase-Targeting agents. Bioorganic & Medicinal Chemistry, 11 (8). pp. 1809-1820.

Lia, D. and Zhao, B. and Sim, S.P and Li, T.K and Liu, A. and Liu, L.F. and LaVoie, E.J. (2002) 2,3-Dimethoxybenzo[i]phenanthridines_ topoisomerase I-targeting anticancer agents. Bioorganic & Medicinal Chemistry, 11 (4). pp. 521-528.

Sim, S.P and Liu, L.F. (2001) Nucleolytic Cleavage of the Mixed Lineage Leukemia Breakpoint Cluster Region during Apoptosis. The Journal of Biological Chemistry, 276. pp. 31591-31595.

Rangarajan, M. and Kim, J.S. and Jin, S. and Sim, S.P and Liu, A. and Pilch, D.S. and Liu, L.F. and LaVoie, E.J. (2000) 2″-Substituted 5-phenylterbenzimidazoles as topoisomerase I poisons. Bioorganic & Medicinal Chemistry, 8 (6). pp. 1371-1382.

Jin, S. and Kim, J.S. and Sim, S.P and Liu, A. and Pilch, D.S. and Liu, L.F. and LaVoie, E.J. (2000) Heterocyclic bibenzimidazole derivatives as topoisomerase I inhibitors. Bioorganic & Medicinal Chemistry Letters , 10 (8). pp. 719-723.

Sim, S.P and Pilch, D.S. and Liu, L.F. (2000) Site-Specific Topoisomerase I-Mediated DNA Cleavage Induced by Nogalamycin: A Potential Role of Ligand-Induced DNA Bending at a Distal Site. Biochemistry, 39 (32). pp. 9928-9934.

Rangarajan, M. and Kim, J.S. and Sim, S.P and Liu, A. and Liu, L.F. and LaVoie, E.J. (2000) Topoisomerase I inhibition and cytotoxicity of 5-Bromo- and 5-Phenylterbenzimidazoles. Bioorganic & Medicinal Chemistry, 8 (11). pp. 2591-2600.