The study of the reaction of morpholine with aryl halide and aliphatic halide

Dorairaaj, A/L Sivasubramaniam (2013) The study of the reaction of morpholine with aryl halide and aliphatic halide. [Final Year Project Report] (Unpublished)

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Abstract

This study was aimed to synthesized the morpholine derivatives by the cross coupling reaction between morpholine and an aryl halide. The reaction of morpholine with 4-bromobenzaldhyde and 4-bromoanisole. When morpholine reacted with 4-bromoanisole, the reaction was failed but morpholine reacted with 4-bromobenzaldehyde produced 4-morpholine-4-yl-benzaldehyde, which showed that the reaction was successful. The reaction of morpholine with 4-bromobenzaldehyde was compared in the presence and absence of the copper(I) iodide which act as a catalyst. The GC result showed that the conversion of the product without catalyst was much more higher than the reaction with catalyst under the same condition. The side product also was discovered in the reaction without catalyst, the morpholine actually was attacked to the carbon in the carbonyl group of 4-bromobenzaldehyde to produce 4-bromobenzoic acid,morpholide.

Item Type: Final Year Project Report
Additional Information: Project Report (B.Sc.) -- Universiti Malaysia Sarawak, 2013.
Uncontrolled Keywords: Morphology,Biochemistry,Unimas, university,universiti, Borneo, Malaysia, Sarawak,Kuching, Samarahan,ipta,education, undergraduate,postgraduate,research ,Universiti Malaysia Sarawak
Subjects: Q Science > Q Science (General)
Q Science > QD Chemistry
Q Science > QH Natural history > QH301 Biology
Divisions: Academic Faculties, Institutes and Centres > Faculty of Resource Science and Technology
Depositing User: Karen Kornalius
Date Deposited: 20 May 2015 04:37
Last Modified: 15 Sep 2015 01:38
URI: http://ir.unimas.my/id/eprint/7619

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