Gc-Ms Analysis Of Phytochemical Constituents In Leaf Extracts Of Neolamarckia Cadamba (Rubiaceae) From Malaysia

Mohamed, Zaky Zayed and Fasihuddin Badruddin, Ahmad and Wei-Seng, Ho and Shek-Ling, Pang (2014) Gc-Ms Analysis Of Phytochemical Constituents In Leaf Extracts Of Neolamarckia Cadamba (Rubiaceae) From Malaysia. International Journal of Pharmacy and Pharmaceutical Sciences, 6 (9). ISSN 0975-1491

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Abstract

Neolamarckia cadamba is one of the medicinal plants used in the treatment of various diseases traditionally. This study was conducted to identify the phytochemical constituents of N. cadamba leaf extracts using gas chromatography mass spectrometry (GC-MS). Solvents with increasing polarities viz. hexane, petroleum ether, chloroform, ethyl acetate and methanol were used in this study. The solvent extracts were analyzed using GC-MS and the mass spectra of the compounds found in the respective extract were matched with the National Institute of Standards and Technology (NIST) library. A total of 26 compounds were identified and the major chemical constituents were n-hexadecanoic acid (44.88%), hexadecanoic acid ethyl ester (17.96%) and octadecanoic acid ethyl ester (11.71%). Some of the identified compounds have been reported to possess various biological activities such as antioxidant, antimicrobial, anesthetic, antiseptic, antidiabetic, hypocholesterolemic and etc. The results thus concluded that N. cadamba leaves possess various potent bioactive compounds and is recommended as a plant of phytopharmaceutical importance.

Item Type: Article
Uncontrolled Keywords: Neolamarckia cadamba, Gas chromatography mass spectrometry (GC-MS), Phytochemical, Secondary metabolite, Antioxidant, plants, Universiti Malaysia Sarawak, UNIMAS, university, universiti, Malaysia, Sarawak, Kuching, Samarahan, IPTA, education,undergraduate,postgraduate, research
Subjects: R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
S Agriculture > SB Plant culture
Divisions: Academic Faculties, Institutes and Centres > Faculty of Resource Science and Technology
Depositing User: Karen Kornalius
Date Deposited: 21 Nov 2014 02:11
Last Modified: 11 Sep 2015 08:21
URI: http://ir.unimas.my/id/eprint/5586

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