OncoDaily News Feature: Researchers identified a substantial presence of peripherally induced Treg cells in the tumor microenvironment

Sang Nee, Tan (2025) OncoDaily News Feature: Researchers identified a substantial presence of peripherally induced Treg cells in the tumor microenvironment. [Magazine and Newsletter]

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Abstract

This OncoDaily news feature highlights commentary by John Gordon on the study “Regulatory T cells converted from Th1 cells in tumors suppress cancer immunity via CD39,” published in the Journal of Experimental Medicine. The report summarizes key findings led by Sang-Nee Tan et al., including the identification of peripherally induced Treg cells in the tumor microenvironment, their conversion from Th1 cells via TGF-β signaling, and their CD39-dependent suppression of antitumor immunity.

Item Type: Magazine and Newsletter
Subjects: Q Science > Q Science (General)
R Medicine > R Medicine (General)
Divisions: Academic Faculties, Institutes and Centres > Faculty of Medicine and Health Sciences
Faculties, Institutes, Centres > Faculty of Medicine and Health Sciences
Depositing User: Sang Nee
Date Deposited: 11 Dec 2025 00:36
Last Modified: 11 Dec 2025 00:36
URI: http://ir.unimas.my/id/eprint/50899

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