Phytochemicals from Calophyllum depressinervosum

Nor Hisam, Zamakshshari and Ee, G.C.L. and Daud, S. and Teh, S.S. and Mah, S.H. (2018) Phytochemicals from Calophyllum depressinervosum. Asian Journal of Chemistry, 30 (5). pp. 975-978. ISSN 0970-7077

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Abstract

A phytochemical investigation on the stem bark of Calophyllum depressinervosum resulted in the isolation of four xanthones, one coumarin and one kavalactone which were elucidated to be caloxanthone B (1), caloxanthone I (2), caloxanthone J (3), xanthochymone B (4), calopolynolide B (5) and desmethoxyyangonim (6). The structures of the compounds were elucidated using spectroscopic analysis such as 1D and 2D NMR together with MS technique. The dichloromethane extract of Calophyllum depressinervosum gave good cell viability on RAW246.7 cells for potential antiinflammatory test with an IC50 value of 17.19 ± 0.007 µg/mL.

Item Type: Article
Uncontrolled Keywords: Calophyllum depressinervosum, Xanthone, Coumarin, Kavalactones, Antiinflammatory.
Subjects: Q Science > QD Chemistry
R Medicine > RS Pharmacy and materia medica
Divisions: Academic Faculties, Institutes and Centres > Faculty of Resource Science and Technology
Depositing User: Zamakshshari
Date Deposited: 19 May 2022 01:42
Last Modified: 19 May 2022 01:42
URI: http://ir.unimas.my/id/eprint/38555

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