Synthesis and Characterisation of Piperine-loaded Starch Nanoparticles

Chong, Wan Hong and Chin, Suk Fun and Pang, Suh Cem and Kok, Kuan Ying (2020) Synthesis and Characterisation of Piperine-loaded Starch Nanoparticles. Journal of Physical Science, 31 (1). pp. 57-68. ISSN 2180-4230

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Abstract

This study aimed to explore the potential application of starch nanoparticles as the nanocarriers for the controlled release of piperine. Starch nanoparticles with mean particle sizes ranging from 50 nm to 200 nm have been synthesised as nanocarriers for encapsulation of piperine. Piperine has been successfully loaded onto starch nanoparticles via the in-situ nanoprecipitation method. The loading capacity of piperine was affected by the synthesis conditions such as types and concentrations of surfactants as well as initial piperine concentrations. Under optimum conditions, starch nanoparticles exhibited a maximum piperine loading capacity of 4.74 mg mg–1. Piperine was observed to release out from starch nanoparticles in a slow and steady manner over a period of 168 h under physiological pH.

Item Type: Article
Uncontrolled Keywords: Piperine, starch nanoparticles, nanocarriers, release studies, syhthesis and characterisatio, unimas, university, universiti, Borneo, Malaysia, Sarawak, Kuching, Samarahan, ipta, education, research, Universiti Malaysia Sarawak.
Subjects: Q Science > Q Science (General)
Q Science > QC Physics
Q Science > QD Chemistry
Divisions: Academic Faculties, Institutes and Centres > Faculty of Resource Science and Technology
Depositing User: Gani
Date Deposited: 04 May 2020 13:30
Last Modified: 04 May 2020 13:30
URI: http://ir.unimas.my/id/eprint/29573

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