Genetic Polymorphism of Inflammation Response Genes TNF-α -308G > A and IL-8 -251 T>A and their Influence on Colorectal Cancer Predisposition Risk in Malaysian Population.

Mohd Aminudin, Bin Mustapha and Siti Nurfatimah, Binti Mohd Shahpudin and Ahmad Aizat, Bin Abdul Aziz and Venkatesh R, Naik and Biswal, Mohan Biswal and Zaidi, Bin Zakaria and Shanwani, A. and Mohammad Radzi, A.H. and Ankhathil, Ravindran (2010) Genetic Polymorphism of Inflammation Response Genes TNF-α -308G > A and IL-8 -251 T>A and their Influence on Colorectal Cancer Predisposition Risk in Malaysian Population. Journal of Gastroenterology and Hepatology, 25 (Supp.2). A1-A188. ISSN 1440-1746

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Abstract

Introduction Genes encoding xenobiotic metabolizing enzymes especially CYP1A2 play an important role in determining the out come of carcinogen exposure and Colorectal Cancer susceptibility risk. Functional polymorphisms of G3860A, T739G and C729T of CYP1A2 gene have been identified.

Item Type: Article
Uncontrolled Keywords: Malaysian population and colorectal cancer, Genetic polymorphisms, susceptibility risk, unimas, university, universiti, Borneo, Malaysia, Sarawak, Kuching, Samarahan, ipta, education, research, Universiti Malaysia Sarawak.
Subjects: R Medicine > R Medicine (General)
Divisions: Academic Faculties, Institutes and Centres > Centre for Pre-University Studies
Depositing User: Mustapha
Date Deposited: 08 Jul 2019 03:09
Last Modified: 08 Jul 2019 03:09
URI: http://ir.unimas.my/id/eprint/25628

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