Chemical composition and biological activities of essential oils and extracts from agathis borneensis

Sitti Hawah, Bt Jatri. (2005) Chemical composition and biological activities of essential oils and extracts from agathis borneensis. [Final Year Project Report] (Unpublished)

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Essential oils from bark, heartwood, and resm of Agathis borneensis obtained by hydrodistillation method were analysed by Gas Chromatography/Flame Ionization Detector (GCIFID) and Gas Chromatography/Mass Spectrometry (GCIMS). Resin contents highest essential oils (3.4%, v/w), followed by bark and heat1wood with 0.25% and 0.1 %, respectively. Bark and heartwood of A. borneensis were extracted with methanol using Soxhlet extractor. The crude extract yield for bark and heartwood are 14.31 % and 10.45%, respectively. The crude extracts were then subjected to fractionation on silica gel column chromatography. The five fractions were then analysed on GCIMS. The major compounds identified in bark of A. borneensis are a-copaene, ~-caryophyllene, 1 S cis-calamenene, benzaldehyde and pimaric acid. Meanwhile the majors compound identified in heartwood are ethyl benzene, benzaldehyde, hexadioic acid dioctyl ester, bis 1,2-benzenedicarboxylic acid and stigmast-5-en-3-o1 (3 beta,24S). Toxicity testing on Artemia salina for essential oils and antifungal for crude extracts were carried out. This show that bark oils has a significant toxicity toward A. salina . Antifungal test for crude extracts showed both bark and heartwood have a potential to decrease the fungi growth rate.

Item Type: Final Year Project Report
Additional Information: Project report (B.Sc.) - Universiti Malaysia Sarawak, 2005.
Uncontrolled Keywords: Agathis borneensis, essential oils, crude extracts, gas chromatography, antifungal, unimas, university, universiti, Borneo, Malaysia, Sarawak, Kuching, Samarahan, ipta, education, undergraduate, research, Universiti Malaysia Sarawak
Subjects: Q Science > QD Chemistry
Q Science > QK Botany
Divisions: Academic Faculties, Institutes and Centres > Faculty of Applied and Creative Arts
Depositing User: Saman
Date Deposited: 15 Mar 2018 00:44
Last Modified: 18 Aug 2021 15:51

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