Size controlled fabrication of cellulose nanoparticles for drug delivery applications

Chin, Suk Fun and Fiona Beragai, Jimmy and Pang, Suh Cem (2018) Size controlled fabrication of cellulose nanoparticles for drug delivery applications. Journal of Drug Delivery Science and Technology, 43. pp. 262-266. ISSN 17732247

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Abstract

Spherically shaped cellulose nanoparticles with average particle diameter range between 70 and 365 nm were fabricated from cotton fibers by a simple nanoprecipitation method. The average particle diameter of cellulose nanoparticles could be precisely controlled by modulating the synthesis conditions such as cellulose solution concentration and volume ratio of solvent/non-solvent. Methylene blue (MB) as a model hydrophilic drug was loaded onto cellulose nanoparticles via the in-situ nanoprecipitation process. The loading efficiency and release profile of MB were observed to be affected by the average particle diameter of cellulose nanoparticles. © 2017

Item Type: E-Article
Uncontrolled Keywords: Cellulose, Nanoparticles, Drug carriers, Size controlled, Nanoprecipitation, unimas, university, universiti, Borneo, Malaysia, Sarawak, Kuching, Samarahan, ipta, education, research, Universiti Malaysia Sarawak.
Subjects: Q Science > Q Science (General)
Divisions: Academic Faculties, Institutes and Centres > Faculty of Resource Science and Technology
Depositing User: Ibrahim
Date Deposited: 13 Feb 2018 08:20
Last Modified: 13 Feb 2018 08:30
URI: http://ir.unimas.my/id/eprint/19597

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