Synthesis and antibacterial study of organotin(IV) complexes containing hydrazinopyridine ligand [Sintesis dan kajian antibakteria kompleks organostanum(IV) yang mengandungi ligan hidrazinopiridin]

Dayang Norafizan, binti Awang Chee and Monica Lulo, Rodis and Norziah, Saat and Zainab, Ngaini and Ainaa Nadiah, Abdul Halim (2017) Synthesis and antibacterial study of organotin(IV) complexes containing hydrazinopyridine ligand [Sintesis dan kajian antibakteria kompleks organostanum(IV) yang mengandungi ligan hidrazinopiridin]. Malaysian Journal of Analytical Sciences, 21 (5). pp. 1143-1150. ISSN 13942506

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Abstract

Nowadays, the studies on organotin(IV) complexes with hydrazone ligand become more interesting due to their potential in various applications including medicinal area. In our recent studies, four new organotin(IV) complexes MeSnCl2(C12H12N4) (2), BuSnCl2(C12H12N4) (3), PhSnCl2(C12H12N4) (4) and Ph2SnCl(C12H12N4) (5) were synthesized by the direct reaction of methyl-2-pyridylketone-2-hydrazinopyridine ligand (1) and organotin(IV) chloride(s) in absolute methanol. These complexes have been characterized by UV-Visible, FT-IR, 1H and 13C NMR spectroscopies. All of the synthesized compounds were screened for antibacterial activity against Escherichia coli and Staphylococcus aureus. However, the complexes showed weak activity against the bacteria compared to the free ligand.

Item Type: Article
Uncontrolled Keywords: hydrazone ligand, spectral studies, coordination, biological potential, unimas, university, universiti, Borneo, Malaysia, Sarawak, Kuching, Samarahan, ipta, education, research, Universiti Malaysia Sarawak
Subjects: Q Science > QD Chemistry
Divisions: Academic Faculties, Institutes and Centres > Faculty of Resource Science and Technology
Depositing User: Ibrahim
Date Deposited: 31 Jan 2018 07:05
Last Modified: 31 Jan 2018 07:05
URI: http://ir.unimas.my/id/eprint/18937

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