Gene expression study on tumour suppressor gene rassfi isoforms and selected inflammatory cytokines in bladder carcinoma

Nur Diana, Binti Anuar (2011) Gene expression study on tumour suppressor gene rassfi isoforms and selected inflammatory cytokines in bladder carcinoma. Masters thesis, Universiti Malaysia Sarawak, (UNIMAS).

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Abstract

Bladder carcinoma (BC) arises as a result of deregulation in oncogene and tumor suppressor gene. Loss of heterozygosity at chromosome region 3p has become common in most cancer development. A tumour suppessor gene, RASSF1 located at this particular egion has been reported to be hypermethylated in most cancer including the bladder and has been a major targeted for tumour suppressor. However, this gene has known to have 7 alternative isoforms which might have different function in bladder tumourigenicity. In this study we aimed to explore the expression status of RASSF1 isofoms in BC biopsy as an effort to explore its role in BC progression.

Item Type: Thesis (Masters)
Additional Information: Thesis (M.Sc.) -- Universiti Malaysia Sarawak, 2011.
Uncontrolled Keywords: Tumor, Cancer,unimas, university, universiti, Borneo, Malaysia, Sarawak, Kuching, Samarahan, ipta, education, Postgraduate, research, Universiti Malaysia Sarawak
Subjects: R Medicine > RB Pathology
Divisions: Academic Faculties, Institutes and Centres > Faculty of Medicine and Health Sciences
Depositing User: Karen Kornalius
Date Deposited: 03 May 2016 01:53
Last Modified: 14 May 2020 04:42
URI: http://ir.unimas.my/id/eprint/11816

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