Synthesis, characterization and antibacterial activity of bis thiourea derivatives

Jayakumar, Ponniasalan (2015) Synthesis, characterization and antibacterial activity of bis thiourea derivatives. [Final Year Project Report] (Unpublished)

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Abstract

A series of bisthiourea derivatives were succesfully synthesized by reaction of benzene-1, 4 dicarbonyl isothiocyanate intermediates and isophthaloyl dichloride, with a series of aromatic amine at ortho, meta and para position. The structure of synthesised compound characterized by infra-red spectroscopy (FTIR), 1H Nuclear magnetic resonances, and 13C Nuclear magnetic resonances. The synthesised compounds were screened for their antibacterial properties using Gram-negative bacteria Escherichia coli (E.coli) by using disc diffusion method. All of synthesized series showed negative results towards antibacterial activity.

Item Type: Final Year Project Report
Additional Information: Project Report (B.Sc.) -- Universiti Malaysia Sarawak, 2015.
Uncontrolled Keywords: unimas, university, universiti, Borneo, Malaysia, Sarawak, Kuching, Samarahan, ipta, education, undergraduate, research, Universiti Malaysia Sarawak, thiourea, E.coli, Antibacterial activity, Amine, Spectroscopy
Subjects: R Medicine > RV Botanic, Thomsonian, and eclectic medicine
Divisions: Academic Faculties, Institutes and Centres > Faculty of Resource Science and Technology
Depositing User: Karen Kornalius
Date Deposited: 21 Mar 2016 08:00
Last Modified: 21 Mar 2016 08:00
URI: http://ir.unimas.my/id/eprint/11053

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