Elevation of dopamine level reduces hostseeking activity in the adult female mosquito Aedes albopictus

Yuki, Fukumitsu and Keiichi, Irie and Tomomitsu, Satho and Hitoshi, Aonuma and Hamady, Dieng and Abu Hassan, Ahmad and Yukihiko, Nakashima and Kenichi, Mishima and Nobuhiro, Kashige and Fumio, Miake (2012) Elevation of dopamine level reduces hostseeking activity in the adult female mosquito Aedes albopictus. Parasites & Vectors, 5 (1). ISSN 1756-3305

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Official URL: https://www.researchgate.net/publication/224938134...

Abstract

Background: Mosquito-borne viruses are transmitted to human hosts via blood-feeding behavior of female mosquitoes. Female mosquitoes seek a host to take blood meals (host-seeking behavior). In order to prevent virus infections, it is important to understand how they modulate host-seeking behavior. Dopamine (DA) in the central nervous system acts as a neuromediator that regulates a variety of behaviors in insects. In female mosquitoes, host-seeking behavior increases when DA levels in the head decline after emergence. However, it remains unclear whether DA directly modulates host-seeking behavior in female mosquitoes. The aim of this study was to examine whether changes in DA levels in the head affects host-seeking activity in the adult female mosquito Aedes albopictus (Ae. albopictus). Findings: We compared host-seeking behavior in one group of emerging female adults treated with L-β-3,4-dihydroxyphenylalanine (L-DOPA), the precursor of DA, (L-DOPA group), with that in an untreated control (control group) after confirming elevation of head DA in L-DOPA group by using high-performance liquid chromatography. The content of head DA in L-DOPA group significantly remained higher than that in controls on all days examined. The host-seeking activity in the control group showed a gradual increase over the 6-day experimental period. In contrast, there was no such increase in the host-seeking activity in the L-DOPA group. Therefore, the host-seeking activity of L-DOPA group was significantly lower than that of the controls between day 3 and 6 post-emergence. Conclusion: Our results indicate that elevation of DA level reduces host-seeking activity in adult female mosquito Ae. albopictus.

Item Type: Article
Uncontrolled Keywords: Host-seeking behavior, Dopamine, Aedes albopictus, research, Universiti Malaysia Sarawak, unimas, university, universiti, Borneo, Malaysia, Sarawak, Kuching, Samarahan, ipta, education
Subjects: S Agriculture > SF Animal culture
Divisions: Academic Faculties, Institutes and Centres > Institute of Biodiversity and Environmental Conservation
Depositing User: Karen Kornalius
Date Deposited: 19 Jan 2016 02:26
Last Modified: 19 Jan 2016 02:26
URI: http://ir.unimas.my/id/eprint/10246

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