The Antibacterial Activity of Titanium Dioxide and Copper Oxide Derivatives

Nur Liyana, Masri (2018) The Antibacterial Activity of Titanium Dioxide and Copper Oxide Derivatives. [Final Year Project Report] (Unpublished)

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Abstract

Titanium dioxide is a most widely used semiconductor as a stable photocatalyst. It can only be activated with the presence of ultraviolet(UV) light. Copper is doped onto titanium dioxide to increase the absorption edge of the wavelength. By doping copper to titanium dioxide, the antibacterial properties of titanium dioxide can be examined in visible light condition. The emergence of antibiotic resistance bacteria reduces the efficiency of the current antibacterial treatment. This increase the urge to find an alternative way to reduce the infections caused by these pathogenic bacteria. The purpose of this study is to evaluate the antibacterial activity of titanium dioxides doped with copper oxide derivatives. The pathogenic bacteria tested are Escherichia coli 0157:H7, Vibrio cholera, Listeria monocytogenes and Bacillus cereus. The result obtains showed that compound with ratio copper to titanium dioxide 2: 1 showed the lowest minimum bactericidal concentration (MBC) for all the strains tested. Three tested compounds with different composition of copper to titanium dioxide ratio (I: 1, 1 :2, 2: 1 ), show antibacterial activity. Pure titanium dioxide also tested in visible light condition, but there is no antibacterial activity recorded. The results showed that the doped compounds are more efficient in killing Gram positive bacteria compared to Gram negative bacteria. The antibacterial activity of the compound is tested using microdilution technique.

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