Non-newtonian blood flow behaviour in microchannels-application in medical industry

Yana Shaheera, Yunos (2015) Non-newtonian blood flow behaviour in microchannels-application in medical industry. [Final Year Project Report] (Unpublished)

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Abstract

Blood is a complex suspension that demonstrates non-Newtonian rheological characteristics. The study of hemorheology has been of great interest in the fields of biomedical engineering and medical researches for many years. Micro-channel such as micro-needle has been an expanding medical technology in recent years due to their ability to penetrate tissue and deliver therapy with minimal invasiveness and patient discomfort. Micro-channel geometries have been used to study the inertial focusing behaviour of particles suspended as variations in design have allowed for enhanced fluid delivery. This manuscript focuses on the fluid flow aspects of the design which has four different shape of channel, characterizing the contributions to hydraulic resistance from the geometric parameters of the micro-channels and the inner surface roughness of the channel which is made from different type of material. Simulations using COMSOL consisted of measuring the flow rate of blood through a relevant range of channel lengths, channel diameters, shape of channel and also material of the channel. The objectives of the study are to investigate the theoretical principles of a blood as a nonNewtonian fluid used for measuring velocity inflow of micro-needles of different type of inner design with different properties and to investigate the effect of non-Newtonian on the blood rheology and flow patterns. The discussion will also include the comparisons of flow velocity in the micro-needle in delivering drug and blood. The micro-needle geometry is successfully designed to improve the flow performance and potentially the micro-needle to deliver drug and blood efficiency.

Item Type: Final Year Project Report
Additional Information: Project Report (B.Sc) --University Malaysia Sarawak, 2015.
Uncontrolled Keywords: Manufactures, Non-Newtonian fluids, unimas, university, universiti, Borneo, Malaysia, Sarawak, Kuching, Samarahan, ipta, education, undergraduate, , research, Universiti Malaysia Sarawak.
Subjects: T Technology > T Technology (General)
T Technology > TJ Mechanical engineering and machinery
Divisions: Academic Faculties, Institutes and Centres > Faculty of Engineering
Faculties, Institutes, Centres > Faculty of Engineering
Depositing User: Gani
Date Deposited: 08 Jul 2019 02:01
Last Modified: 13 Mar 2024 08:01
URI: http://ir.unimas.my/id/eprint/25626

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