%PDF-1.7
%
1 0 obj
<<
/AcroForm 2 0 R
/Metadata 3 0 R
/Names 4 0 R
/OCProperties <<
/D <<
/OFF []
/Order [5 0 R]
/RBGroups []
>>
/OCGs [5 0 R]
>>
/OpenAction [6 0 R /FitH 804]
/Outlines 7 0 R
/PageLabels <<
/Nums [0 8 0 R]
>>
/PageMode /UseOutlines
/Pages 9 0 R
/SaveStreams <<
/Q 10 0 R
/q 11 0 R
>>
/Type /Catalog
>>
endobj
12 0 obj
<<
/Author (Shu Pin Yu)
/CreationDate (D:20181124105948Z)
/Creator (Elsevier)
/CrossMarkDomains#5B1#5D (elsevier.com)
/CrossMarkDomains#5B2#5D (sciencedirect.com)
/CrossmarkDomainExclusive (true)
/CrossmarkMajorVersionDate (2010-04-23)
/ElsevierWebPDFSpecifications (6.5)
/Keywords (Japanese encephalitis virus; Transcriptome; RNA microarray; Proinflammatory mediators; Neuronal infection; CXCL11; RIG-1; MDA5; )
/ModDate (D:20181124105948Z)
/Subject (Virology, 527 \(2018\) 107-115. doi:10.1016/j.virol.2018.10.015)
/Title (Neuronal transcriptomic responses to Japanese encephalitis virus infection with a special focus on chemokine CXCL11 and pattern recognition receptors RIG-1 and MDA5)
/doi (10.1016/j.virol.2018.10.015)
/robots (noindex)
>>
endobj
2 0 obj
<<
/DA (/Helv 0 Tf 0 g )
/DR <<
/Encoding <<
/PDFDocEncoding 13 0 R
>>
/Font <<
/Helv 14 0 R
/ZaDb 15 0 R
>>
>>
/Fields []
>>
endobj
3 0 obj
<<
/Length 7249
/Subtype /XML
/Type /Metadata
>>
stream
application/pdf
doi:10.1016/j.virol.2018.10.015
Neuronal transcriptomic responses to Japanese encephalitis virus infection with a special focus on chemokine CXCL11 and pattern recognition receptors RIG-1 and MDA5
Shu Pin Yu
Kien Chai Ong
David Perera
Kum Thong Wong
Japanese encephalitis virus
Transcriptome
RNA microarray
Proinflammatory mediators
Neuronal infection
CXCL11
RIG-1
MDA5
Elsevier Inc.
Virology, 527 (2018) 107-115. doi:10.1016/j.virol.2018.10.015
journal
Virology
© 2018 Elsevier Inc. All rights reserved.
0042-6822
527
107-115
107
115
10.1016/j.virol.2018.10.015
https://doi.org/10.1016/j.virol.2018.10.015
2010-04-23
true
10.1016/j.virol.2018.10.015
elsevier.com
sciencedirect.com
6.5
10.1016/j.virol.2018.10.015
2010-04-23
true
noindex
elsevier.com
sciencedirect.com
VoR
Elsevier
2018-11-24T10:59:48Z
2018-11-24T10:59:48Z
2018-11-24T10:59:48Z
True
Japanese encephalitis virus; Transcriptome; RNA microarray; Proinflammatory mediators; Neuronal infection; CXCL11; RIG-1; MDA5;
uuid:393bf3a2-979a-4d9c-b2f5-57176c951f13
uuid:05974305-9c1c-4303-bec0-03d70681cd24
endstream
endobj
4 0 obj
<<
/Dests 16 0 R
/EmbeddedFiles 17 0 R
/JavaScript 18 0 R
>>
endobj
5 0 obj
<<
/Intent [/View /Design]
/Name (Layer 1)
/Type /OCG
/Usage 19 0 R
>>
endobj
6 0 obj
<<
/Annots [20 0 R 21 0 R 22 0 R 23 0 R 24 0 R 25 0 R 26 0 R 27 0 R 28 0 R 29 0 R
30 0 R 31 0 R 32 0 R 33 0 R 34 0 R 35 0 R 36 0 R 37 0 R 38 0 R 39 0 R
40 0 R 41 0 R 42 0 R 43 0 R]
/Contents 44 0 R
/CropBox [0 0 595.276 793.701]
/MediaBox [0 0 595.276 793.701]
/Parent 9 0 R
/QInserted true
/Resources <<
/ColorSpace <<
/CS0 [/Separation /macblue /DeviceCMYK 45 0 R]
>>
/ExtGState <<
/GS0 46 0 R
/GS1 47 0 R
>>
/Font 48 0 R
/ProcSet [/PDF /Text /ImageC]
/XObject <<
/Fm0 49 0 R
/Im0 50 0 R
/Im1 51 0 R
>>
>>
/Rotate 0
/Type /Page
>>
endobj
7 0 obj
<<
/Count 21
/First 52 0 R
/Last 52 0 R
>>
endobj
8 0 obj
<<
/P ()
/S /D
/St 107
>>
endobj
9 0 obj
<<
/Count 9
/Kids [6 0 R 53 0 R 54 0 R 55 0 R 56 0 R 57 0 R 58 0 R 59 0 R 60 0 R]
/Type /Pages
>>
endobj
10 0 obj
<<
/Length 3
>>
stream
Q
endstream
endobj
11 0 obj
<<
/Length 3
>>
stream
q
endstream
endobj
13 0 obj
<<
/Differences [24 /breve /caron /circumflex /dotaccent /hungarumlaut /ogonek /ring /tilde 39
/quotesingle 96 /grave 128 /bullet /dagger /daggerdbl /ellipsis /emdash /endash
/florin /fraction /guilsinglleft /guilsinglright /minus /perthousand /quotedblbase /quotedblleft /quotedblright /quoteleft
/quoteright /quotesinglbase /trademark /fi /fl /Lslash /OE /Scaron /Ydieresis /Zcaron
/dotlessi /lslash /oe /scaron /zcaron 160 /Euro 164 /currency 166
/brokenbar 168 /dieresis /copyright /ordfeminine 172 /logicalnot /.notdef /registered /macron
/degree /plusminus /twosuperior /threesuperior /acute /mu 183 /periodcentered /cedilla /onesuperior
/ordmasculine 188 /onequarter /onehalf /threequarters 192 /Agrave /Aacute /Acircumflex /Atilde
/Adieresis /Aring /AE /Ccedilla /Egrave /Eacute /Ecircumflex /Edieresis /Igrave /Iacute
/Icircumflex /Idieresis /Eth /Ntilde /Ograve /Oacute /Ocircumflex /Otilde /Odieresis /multiply
/Oslash /Ugrave /Uacute /Ucircumflex /Udieresis /Yacute /Thorn /germandbls /agrave /aacute
/acircumflex /atilde /adieresis /aring /ae /ccedilla /egrave /eacute /ecircumflex /edieresis
/igrave /iacute /icircumflex /idieresis /eth /ntilde /ograve /oacute /ocircumflex /otilde
/odieresis /divide /oslash /ugrave /uacute /ucircumflex /udieresis /yacute /thorn /ydieresis]
/Type /Encoding
>>
endobj
14 0 obj
<<
/BaseFont /Helvetica
/Encoding 13 0 R
/Name /Helv
/Subtype /Type1
/Type /Font
>>
endobj
15 0 obj
<<
/BaseFont /ZapfDingbats
/Name /ZaDb
/Subtype /Type1
/Type /Font
>>
endobj
16 0 obj
<<
/Kids [61 0 R 62 0 R 63 0 R]
>>
endobj
17 0 obj
<<
>>
endobj
18 0 obj
<<
>>
endobj
19 0 obj
<<
/CreatorInfo <<
/Creator (Adobe Illustrator 22.1)
/Subtype /Artwork
>>
>>
endobj
20 0 obj
<<
/A <<
/S /URI
/URI (http://www.sciencedirect.com/science/journal/00426822)
>>
/Border [0 0 0]
/Rect [322.242 723.798 369.978 731.792]
/Subtype /Link
/Type /Annot
>>
endobj
21 0 obj
<<
/A <<
/S /URI
/URI (https://www.elsevier.com/locate/virology)
>>
/Border [0 0 0]
/Rect [269.348 668.012 410.06 676.006]
/Subtype /Link
/Type /Annot
>>
endobj
22 0 obj
<<
/A <<
/S /URI
/URI (https://doi.org/10.1016/j.virol.2018.10.015)
>>
/Border [0 0 0]
/Rect [37.587 730.091 37.587 742.053]
/Subtype /Link
/Type /Annot
>>
endobj
23 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [90.142 563.527 94.167 574.129]
/Subtype /Link
/Type /Annot
>>
endobj
24 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [169.285 563.527 173.707 574.129]
/Subtype /Link
/Type /Annot
>>
endobj
25 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [241.285 563.527 244.97 574.129]
/Subtype /Link
/Type /Annot
>>
endobj
26 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [336.983 563.527 341.008 574.129]
/Subtype /Link
/Type /Annot
>>
endobj
27 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [343.219 564.661 347.187 575.206]
/Subtype /Link
/Type /Annot
>>
endobj
28 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [158.23 251.15 288.68 259.143]
/Subtype /Link
/Type /Annot
>>
endobj
29 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [37.587 240.718 55.559 248.712]
/Subtype /Link
/Type /Annot
>>
endobj
30 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [130.961 188.391 173.82 196.384]
/Subtype /Link
/Type /Annot
>>
endobj
31 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [140.712 167.471 212.258 175.465]
/Subtype /Link
/Type /Annot
>>
endobj
32 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [163.105 146.551 266.23 154.545]
/Subtype /Link
/Type /Annot
>>
endobj
33 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [494.192 324.397 557.688 332.391]
/Subtype /Link
/Type /Annot
>>
endobj
34 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [306.595 313.965 347.357 321.902]
/Subtype /Link
/Type /Annot
>>
endobj
35 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [391.521 272.069 464.201 280.063]
/Subtype /Link
/Type /Annot
>>
endobj
36 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [505.984 240.718 557.631 248.712]
/Subtype /Link
/Type /Annot
>>
endobj
37 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [306.595 230.23 394.526 238.224]
/Subtype /Link
/Type /Annot
>>
endobj
38 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [539.83 209.31 557.631 217.304]
/Subtype /Link
/Type /Annot
>>
endobj
39 0 obj
<<
/Border [0 0 0]
/Dest
/Rect [306.595 198.879 552.416 206.816]
/Subtype /Link
/Type /Annot
>>
endobj
40 0 obj
<<
/A <<
/S /URI
/URI (https://doi.org/10.1016/j.virol.2018.10.015)
>>
/Border [0 0 0]
/Rect [37.587 75.515 179.773 82.715]
/Subtype /Link
/Type /Annot
>>
endobj
41 0 obj
<<
/A <<
/S /URI
/URI (mailto:wongkt@ummc.edu.my)
>>
/Border [0 0 0]
/Rect [97.568 92.069 173.027 99.269]
/Subtype /Link
/Type /Annot
>>
endobj
42 0 obj
<<
/A 64 0 R
/BS <<
/S /S
/Type /Border
/W 0
>>
/Border [0 0 0]
/Rect [244.956 747.911 362.884 760.893]
/Subtype /Link
/Type /Annot
>>
endobj
43 0 obj
<<
/A 65 0 R
/BS <<
/S /S
/Type /Border
/W 0
>>
/Border [0 0 0]
/Rect [499.585 605.96 536.505 623.99]
/Subtype /Link
/Type /Annot
>>
endobj
44 0 obj
[66 0 R 67 0 R 68 0 R 69 0 R 70 0 R 71 0 R 72 0 R 73 0 R 74 0 R]
endobj
45 0 obj
<<
/BitsPerSample 8
/Decode [0 1 0 1 0 1 0 1]
/Domain [0 1]
/Encode [0 254]
/Filter /FlateDecode
/FunctionType 0
/Length 528
/Range [0 1 0 1 0 1 0 1]
/Size [255]
>>
stream
h,WP n[QQ[uww#} BT(P5*(kED^ p5P-Ԫۨ]]sPwQ^諅/4(CZâ%B455N:xtiF: