Synthesis, spectral characterization and cytotoxic activity of 3D-transition metal complexes with O-vanillin benzoylhydrazone ligand

Husna Sarfina, Bt Husain (2012) Synthesis, spectral characterization and cytotoxic activity of 3D-transition metal complexes with O-vanillin benzoylhydrazone ligand. [Final Year Project Report] (Unpublished)

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Abstract

Six new Mn(II), Fe(II), Co(II), Ni(II), Cu(II) and Zn(II) complexes (2-7) of o-vanillin benzoylhydrazone ligand (1) have been synthesized and characterized. The ligand (1) and its 3dmetal complexes (2-7) were characterized by elemental analysis, molar conductivity, UVVisible, FT-IR and 1H NMR spectroscopic studies. The spectroscopic data of the complexes (2- 7) suggested that the ligand (1) is acted as a dinegative tridentate chelating system and is coordinated to central metal(II) atom through phenoxide-O, atomethine-N and carboxylate-O atoms. Four coordinated molecular structure has been proposed for the synthesized 3d-transition metal complexes. The ligand (1) and its metal complexes (2-7) have also been tested for their cytotoxicity and found to be less active against Artemia salina.

Item Type: Final Year Project Report
Additional Information: Project Report (B.Sc.) -- Universiti Malaysia Sarawak, 2012.
Uncontrolled Keywords: Hydrazones, Diazo compounds, Universiti Malaysia Sarawak, UNIMAS, university, university, education, IPTA, research, Sarawak, Malaysia, kuching, samarahan, borneo, undergraduate
Subjects: Q Science > Q Science (General)
Q Science > QD Chemistry
Divisions: Academic Faculties, Institutes and Centres > Faculty of Resource Science and Technology
Faculties, Institutes, Centres > Faculty of Resource Science and Technology
Depositing User: Karen Kornalius
Date Deposited: 13 May 2015 04:45
Last Modified: 27 Oct 2023 02:35
URI: http://ir.unimas.my/id/eprint/7444

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