Splenic tuberculosis presenting as pyrexia of unknown origin

Hamizah, R and Rohana, AG and Anwar, SA and Ong, TZ and Hamzaini, AH and Zulkarnaen, AN (2007) Splenic tuberculosis presenting as pyrexia of unknown origin. Medical Journal Malaysia, 62 (1). pp. 70-71.

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Abstract

We report a case of a previously healthy 38-year old lady who presented with prolonged fever and hepatosplenomegaly. Intensive investigations were performed for pyrexia of unknown origin which revealed negative. CT scan of the abdomen showed multiple hypodense lesions which did not respond to broad-spectrum antibiotics. Percutaneous biopsy of the splenic lesion revealed granuloma formation and Langhan's giant cells suggestive of TB. She responded well with anti- TB medication but required extended treatment duration of 24 months due to persistence of the splenic lesion on repeated CT scans. This case illustrates a very rare clinical entity of isolated splenic TB with a therapeutic dilemma following incomplete resolution, despite prolonged treatment.

Item Type: Article
Additional Information: Universiti Malaysia Sarawak, (UNIMAS)
Uncontrolled Keywords: UNIMAS, Universiti Malaysia Sarawak, Splenic tuberculosis, pyrexia,
Subjects: Q Science > Q Science (General)
R Medicine > R Medicine (General)
Divisions: Academic Faculties, Institutes and Centres > Faculty of Medicine and Health Sciences
Depositing User: Karen Kornalius
Date Deposited: 12 May 2014 02:31
Last Modified: 20 Mar 2015 06:01
URI: http://ir.unimas.my/id/eprint/2481

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