Expression Trend of Selected Ribosomal Protein Genes in Nasopharyngeal Carcinoma

Sim, Edmund and Ling, Teck Yee and Tiong, Thung-Sing and Selva, Subramaniam and Khoo, Alan (2012) Expression Trend of Selected Ribosomal Protein Genes in Nasopharyngeal Carcinoma. Malays J Med Sci. 2012 ; 19(4) : 23-30.

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Abstract

Ribosomal proteins are traditionally associated with protein biosynthesis until recent studies that implicated their extraribosomal functions in human diseases and cancers. Our previous studies using GeneFishingTM DEG method and microarray revealed underexpression of three ribosomal protein genes, RPS26, RPS27, and RPL32 in cancer of the nasopharynx. Herein, we investigated the expression pattern and nucleotide sequence integrity of these genes in nasopharyngeal carcinoma to further delineate their involvement in tumourigenesis. The relationship of expression level with clinicopathologic factors was also statistically studied.

Item Type: Article
Additional Information: Universiti Malaysia Sarawak, UNIMAS
Uncontrolled Keywords: NPC; RP; RPL32; RPS26; RPS27; transcript expression, FSTS, 2012, Universiti Malaysia Sarawak, UNIMAS, universiti, university, Borneo, Malaysia, Sarawak, Kuching, Samarahan, IPTA, education, research
Subjects: A General Works > AC Collections. Series. Collected works
A General Works > AC Collections. Series. Collected works

Q Science > Q Science (General)
Divisions: Academic Faculties, Institutes and Centres > Faculty of Resource Science and Technology
Depositing User: Karen Kornalius
Date Deposited: 30 Apr 2014 03:42
Last Modified: 19 Mar 2015 06:40
URI: http://ir.unimas.my/id/eprint/2150

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