Cloning and expression of prM and it's use to distinguish host immune responses against dengue virus and Japanese encephalitis virus infections

Wang, Seok Mui (2001) Cloning and expression of prM and it's use to distinguish host immune responses against dengue virus and Japanese encephalitis virus infections. Masters thesis, Universiti Malaysia Sarawak, (UNIMAS).

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Abstract

All flaviviruses share common epitopes on the envelope protein (E) that results in extensive crossreactions in serological tests. /this makes it difficult to distinguish between immune responses against dengue virus (DENV) and Japanese encephalitis virus (JEV), particularly in regions where these viruses co-circulate. We have demonstrated that DENV and JEV have unique epitopes on the prM. By detecting prM specific IgG, it is possible to distinguish between DENV and JEV infection. Current approach used in seroanalysis of DENV and JEV infections is based on antigens derived from the whole viral antigens.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Japanese B Encephalitis virus, unimas, university, universiti, Borneo, Malaysia, Sarawak, Kuching, Samarahan, ipta, education, Postgraduate, research, Universiti Malaysia Sarawak
Subjects: R Medicine > RA Public aspects of medicine
Divisions: Academic Faculties, Institutes and Centres > Institute of Health and Community Medicine
Depositing User: Saman
Date Deposited: 09 Jun 2017 07:02
Last Modified: 09 Jun 2017 07:02
URI: http://ir.unimas.my/id/eprint/16585

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