Fabrication of cellulose aerogel from sugarcane bagasse as drug delivery carriers

Chin, Sukfun and Jimmy, Fiona Beragai and Pang, Suhcem (2016) Fabrication of cellulose aerogel from sugarcane bagasse as drug delivery carriers. Journal of Physical Science, 27 (3). pp. 159-168. ISSN 16753402

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Abstract

Currently most of the aerogel-based drug delivery carriers are made from non-biodegradable materials, such as silica. In this study, highly porous cellulose aerogels with Brunauer-Emmett-Teller (BET) surface areas that varied between 22 m2 g-1 and 525 m2 g-1 were prepared from a sugarcane bagasse cellulose solution of various concentrations. The potential utility of cellulose aerogels as controlled release carriers was evaluated by loading methylene blue (MB) as a model hydrophilic drug. The MB loading capacity and release kinetic profiles of cellulose aerogels were observed to be substantially influenced by their BET surface areas. Under optimum conditions, a maximum loading capacity of 6.4 mg MB mg-1 cellulose aerogel was achieved with sustained release of MB from cellulose aerogels at physiological pH over a period of 23 h

Item Type: Article
Uncontrolled Keywords: Aerogels; Cellulose; Controlled release; Drug carriers; Sugarcane bagasse, research, Universiti Malaysia Sarawak, unimas, university, universiti, Borneo, Malaysia, Sarawak, Kuching, Samarahan, ipta, education
Subjects: Q Science > QD Chemistry
Divisions: Academic Faculties, Institutes and Centres > Faculty of Resource Science and Technology
Depositing User: Ibrahim
Date Deposited: 16 Feb 2017 07:22
Last Modified: 17 Feb 2017 00:35
URI: http://ir.unimas.my/id/eprint/15302

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