Au decorated ZnO thin film: application to DNA sensing

Foo, K. L. and Hashim, U. and Voon, C. H. and Mohammad, Kashif and Md. Eaqub, Ali (2016) Au decorated ZnO thin film: application to DNA sensing. Microsystem Technologies, 22 (4). pp. 903-910. ISSN 1432-1858

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Abstract

Here we reported the gold nanoparticles (GNPs) decorated ZnO thin films based biosensor for the detection of pork DNA hybridization. Label-free DNA detection is increasingly important in bio diagnostics, food analysis and forensic investigations. The capacitance, permittivity and impedance profiles of the biosensor clearly differentiated the complementary and non-complementary target DNA detection using low-cost dielectric analyzer. In this study, GNPs were used to create an attachment surface between the ZnO thin films and the thiol-modified probe DNA and to enhance the sensitivity of the biosensor up to ~59 %. The ZnO thin films and 35 ± 5 nm in diameters of GNP-coating on their surfaces were confirmed with various types of measurement such as FESEM, XRD, EDX and UV–Vis spectroscopy.

Item Type: Article
Uncontrolled Keywords: old nanoparticles (GNPs), DNA hybridization, ZnO thin films, research, Universiti Malaysia Sarawak, unimas, university, universiti, Borneo, Malaysia, Sarawak, Kuching, Samarahan, ipta, education
Subjects: T Technology > T Technology (General)
Divisions: Academic Faculties, Institutes and Centres > Faculty of Engineering
Depositing User: Karen Kornalius
Date Deposited: 26 Jan 2016 03:35
Last Modified: 21 Oct 2016 01:34
URI: http://ir.unimas.my/id/eprint/10321

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